| 脾切除术对肝癌发生的影响 |
| |
| 引用本文： | 董晓平杨帆周倜姜巍陈勇.脾切除术对肝癌发生的影响[J].现代生物医学进展,2011,11(4):715-718. |
| |
| 作者姓名： | 董晓平杨帆周倜姜巍陈勇 |
| |
| 作者单位： | 第四军医大学西京医院肝胆外科,陕西,西安,710032 |
| |
| 摘 要： | 目的:探讨脾切除术对肝炎后肝硬化脾亢患者的肝癌发生发展的影响。方法:回顾性研究369名肝硬化脾亢伴或不伴肝癌患者,经倾向性得分匹配方法(PS法)均衡分为无脾切除组(246例)和脾切除组(123例),分别比较脾切组中脾切除术对患者肝功能的影响和两组间肝癌发生率的差异。结果:脾切除术后患者AST、ALT在短期内有轻微升高,WBC和PLT记数明显增加,血清TBIL和PT也都降低。无脾切除组和脾切除组的肝癌发生率分别为33.33%和12.26%,卡方检验结果P<0.05,有统计学意义。结论:脾切除术不但可以改善肝硬化肝癌患者的肝功能,还可以降低肝硬化脾亢患者肝癌发生的危险。
|
| 关 键 词： | 脾切除术 肝炎后肝硬化 肝癌发生 |
Effect of Splenectomy on Hepatocacinogensis |
| |
| DONG Xiao-ping,YANG Fan,ZHOU Ti,JIANG Wei,CHEN Yong.Effect of Splenectomy on Hepatocacinogensis[J].Progress in Modern Biomedicine,2011,11(4):715-718. |
| |
| Authors: | DONG Xiao-ping YANG Fan ZHOU Ti JIANG Wei CHEN Yong |
| |
| Institution: | DONG Xiao-ping,YANG Fan,ZHOU Ti,JIANG Wei,CHEN Yong(Department of Hepatobiliary Surgery,Xijing Hospital,FMMU,Xi'an 710032,China) |
| |
| Abstract: | Objective:To explore the impact of splenectomy to hepatocacinogensis in hepatitis cirrhosis patients with hyper-splenism.Methods:369 patients with hypersplenism secondry to liver cirrhosis with or without hepatocellular carcinoma(HCC) were divided into 2 cohorts,non-splenectomy cohort with 246 patients and splenectomy cohort with 123 patients.To compared the effects of liver function before and after operation in splenectomy cohort,and study the different incidence of HCC between the two cohorts,re-spective... |
| |
| Keywords: | Splenectomy Hepatitis cirrhosis Hepatocacinogensis |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《现代生物医学进展》浏览原始摘要信息 |
| 点击此处可从《现代生物医学进展》下载免费的PDF全文 |
|
