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雾化吸入糖皮质激素治疗AECOPD的临床观察
引用本文:王辉,张红超,张江丽.雾化吸入糖皮质激素治疗AECOPD的临床观察[J].现代生物医学进展,2011,11(4):735-737.
作者姓名:王辉  张红超  张江丽
作者单位:1. 广东边防总队海警第一支队卫生队,广东,广州,510660
2. 北京空军总医院心胸外科,北京,100142
3. 北京军区联勤部药品仪器检验所,北京,100071
摘    要:目的:探讨雾化吸入糖皮质激素治疗慢性阻塞性肺病急性加重期(AECOPD)的临床效果。方法:60例AECOPD患者随机分为治疗组和对照组,对照组给予抗感染、吸氧、化痰等常规治疗,治疗组在常规治疗的基础上给予糖皮质激素雾化吸入治疗,连续治疗14d后评价临床疗效,观察治疗前后两组患者的临床症状和肺功能改善情况。结果:治疗组临床疗效有效率为96.7%,高于对照组(80.0%),相比较有显著性差异(P<0.05);治疗组临床症状评分和呼吸困难评分与治疗前和对照组比较显著下降,相比较有显著性差异(P<0.05);治疗组FEV1、FEV水平与治疗前和对照组比较显著上升,肺功能改善显著,相比较有显著性差异(P<0.05)。结论:雾化吸入糖皮质激素治疗AECOPD疗效肯定,值得临床推广应用

关 键 词:慢性阻塞性肺病  急性加重期  糖皮质激素  雾化吸入

Clinical Observation on Inhalation Efficacy of Corticosteroid for Acute Exacerbation of COPD
WANG Hui,ZHANG Hong-chao,ZHANG Jiang-li.Clinical Observation on Inhalation Efficacy of Corticosteroid for Acute Exacerbation of COPD[J].Progress in Modern Biomedicine,2011,11(4):735-737.
Authors:WANG Hui  ZHANG Hong-chao  ZHANG Jiang-li
Institution:WANG Hui1,ZHANG Hong-chao2,ZHANG Jiang-li3(1 First Detachment Health Team of China Goast guard of Guangdong Border Defence Corps,Guangzhou,510660,2 Department of Cardiothoracic Surgery,Air Force General Hospital of Beijing,PLA,100142,3 Test House of Drugs and equipment,Lianqin Department of Beijing Military Region,100071)
Abstract:Objective:To evaluate the inhalation efficacy of corticosteroid in acute exacerbation of chronic obstructive pulmonary disease(AECOPD)therapy.Methods:A total of 60 patients with AECOPD were randomly divided into treatment group and control group.The control group was conventional treatment of antibiotics,oxygen,phlegm,and so on.On the basis of conventional treatment the treatment group were given inhaled corticosteroid therapy.14d after continuous treatment the clinical effect was evaluated,the clini-cal sy...
Keywords:chronic obstructive pulmonary disease  acute exacerbation  corticosteroid  inhalation  
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