依达拉奉治疗急性脑出血的临床疗效及对血浆MMP-9水平的影响

目的:观察依达拉奉治疗急性脑出血的临床疗效和对血浆基质金属蛋白酶-9(MMP-9)水平的影响。方法:60例急性脑出血患者随机分为治疗组和对照组各30例。对照组给予常规治疗,治疗组在对照组治疗基础上加用依达拉奉,并在治疗后24h内和14d进行神经功能缺损评分及血浆MMP-9水平测定。结果:治疗组神经功能缺损评分、血浆MMP-9水平较对照组降低(P<0.05、P<0.01)。结论:依达拉奉可改善急性脑出血患者神经功能,可能与降低MMP-9水平有关。

MMP-9 changes after acute intracerebral hemorrhage and intervention study with edaravone injection

Objective:To observe the clinical efficacy of edaravone for acute intracerebral hemorrhage and its impact on serum content of MMP-9.Methods:A total of 60 patients were enrolled :30(control group) were randomly assigned to receive routine therapy alone,and 30(trial group) to receive routine therapy plus edaravone.The nerve f unction deficiency scores,serum content of MMP-9 were compared 14d before and after treatment.Results:In the trial group as compared with the control group,the nerve function deficien-cy...