Skin cancer: lights on genome lesions |
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Authors: | Lima-Bessa Keronninn M Menck Carlos F M |
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Affiliation: | Department of Microbiology, Institute of Biomedical Sciences, São Paulo, SP, Brazil |
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Abstract: |  Sunlight generates skin damage mainly by inducing DNA lesions in epidermal cells. The recent development of transgenic mice expressing specific photolyases has identified cyclobutane pyrimidine dimers as the major player in ultraviolet-induced damage, including skin cancer. |
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