连续全遮盖法治疗双眼屈光参差性弱视的有效性与安全性分析

目的:探讨连续q全遮盖法治疗双眼屈光参差性弱视的有效性与安全性。方法:选择2014年2月到2016年9月在我院诊治的126例双眼屈光参差性弱视患儿作为研究对象,根据治疗方法的不同分为阿托品组60例与遮盖组66例,遮盖组采用连续全遮盖法治疗,阿托品组给予阿托品治疗,两组都治疗观察3个月。比较两组治疗期间不良反应的发生情况、治疗后的总有效率、最佳矫正视力、电位潜伏期、波幅。结果:两组治疗期间都无严重不良反应发生。治疗后,遮盖组与阿托品组的总有效率分别为98.5%和88.3%,遮盖组的总有效率明显高于阿托品组(P0.05)。两组治疗后的最佳矫正视力都高于治疗前,且遮盖组治疗后的最佳矫正视力也明显高于阿托品组(P0.05)。两组治疗后的电位潜伏期都较治疗前明显缩短,而波幅明显增强(P0.05),且遮盖组治疗后的潜伏期明显短于阿托品组,而波幅显著强于阿托品组(P0.05)。结论:连续全遮盖法治疗双眼屈光参差性弱视具有很好的安全性,能提高患儿的治疗效果,改善视力,促进神经元的兴奋性。

Efficacy and Safety of Continuous Occlusion in the Treatment of Binocular Refractive Aberration

ABSTRACT Objective: To investigate the efficacy and safety of continuous fullocclusion in the treatment of binocular refractive aberration. Methods: From February 2014 to September 2016, 126 cases of binocular refractive aberration in children in our hospital were selected as the research object, all the cases were divided into 60 cases of occlusion and 66 cases of atropine group by different treatment methods. The occlusion group was given the continuous full covering law treatment, the atropine group was given atropine treatment, the treatment cycles in the two groups were 3 months. The incidence of serious adverse reactions during treatment, total effective rate, best corrected visual acuity, latency and amplitude were compared between two groups. Results: There was no serious adverse reaction in the two groups during treatment. The total effective rate of treatment group and the atropine group was 98.5% and 88.3% respectively, and the total effective rate of treatment group was significantly higher than that of the atropine group (P<0.05). The best corrected visual acu- ity of both groups were higher than those before treatment, which was significantly higher in the treatment group than that of atropine group(P<0.05). The latency of both groups after treatment were significantly shorter than those before treatment, and the amplitude were significantly enhanced, and the latency of treatment group was significantly shorter in the treatment group than that of atropine group(P<0.05), while the amplitude was statistically higher(P<0.05). Conclusion: Continuous occlusion is a good method to improve the ther- apeutic effect in the treatment of binocular refractive aberration, it can improve the visual acuity and promote the excitability of neurons.