内镜下黏膜剥除术治疗早期消化道腺瘤性肿瘤的临床疗效分析

目的:探讨内镜下黏膜剥除术治疗早期消化道腺瘤性肿瘤的临床效果。方法:将我院自2015年4月至2018年4月收治的消化道腺瘤性肿瘤患者85例作为研究对象,按照随机抽签法分为研究组43例和对照组42例,研究组使用内镜下黏膜剥除术进行治疗,对照组采用常规内窥镜手术治疗,观察和比较两组患者的临床疗效。结果:两组患者脂肪瘤、平滑肌瘤、间质瘤、异位胰腺和增生性息肉瘤的发生率比较差异无统计学意义(P0.05)。研究组患者病变最大径、创面长径、手术时间和术后住院时间均明显低于对照组,患者出血、穿孔等并发症发生率为4.65%,明显低于对照组(19.05%)。术后随访6个月,研究组无复发,对照组复发率为23.81%,组间比较差异具有统计学意义(P0.05)。结论:早期消化道腺瘤性肿瘤患者行内镜下黏膜剥除术能够提高切除率,缩短手术时间和住院时间,降低患者并发症发生率和复发率。

Analysis of the Clinical Effect of Endoscopic Submucosal Dissection on the Early Stage of Gastrointestinal Adenoma

ABSTRACT Objective: To investigate the clinical effect of endoscopic submucosal dissection on the early stage of gastrointestinal adenoma. Methods: 85 cases of patients with adenomatous tumor of digestive tract admitted from April 2015 to April 2018 were selected as the research subjects. According to the random draw method, 43 cases in the study group were treated by endoscopic submucosal dis- section, and 42 cases in the control group were treated with conventional endoscopic surgery, the clinical efficacy were compared be- tween the two groups. Results: There was no significant difference in the incidence of lipoma, leiomyoma, stromal tumor, ectopic pan- creas and hyperplastic polyposis between the two groups(P>0.05), and the maximum lesion diameter, wound length, operation time and hospital stay were lower in the study group than those in the control group. The incidence of hair disease in study group was 4.65%, which was obviously lower than that of the control group. After 6 months of follow-up, no recurrence was found in the study group, it was significantly lower than that of the control group(23.81%, P<0.05). Conclusion: Endoscopic submucosal dissection can improve the resection rate, shorten the time of operation and stay in hospital, reduce the incidence of complications and recurrence rate.