Cancer proteomics: from signaling networks to tumor markers |
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| Institution: | 1. Joint Protein Structure Laboratory, Ludwig Institute for Cancer Research/ Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia 3050;2. Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia 3001;1. Research scholar, VIT University, Vellore, Tamil Nadu 632014, India;2. Faculty, School of Mechanical and Civil Engineering, MITAOE, Pune 412105, India;3. School of Mechanical Engineering, VIT University, Vellore, Tamil Nadu 632014, India;1. Department of Mechanical Engineering, Graphic Era Deemed to be University, Dehradun, India;2. Department of Mechanical Engineering, School of Technology, GITAM (Deemed to be University), Bengaluru, India;3. Department of Mechanical Engineering, Graphic Era Hill University, Dehradun, India;1. Graphic Era Deemed to Be University, Dehradun, India;2. Center for Research in Engineering and Applied Sciences, UAEM, Av. Universidad, Col. Chamilpa, Cuernavaca, Morelos, Mexico;1. Material Science, Department of Chemistry, Trent University, 1600 West Bank, Peterborough, Ontario K9L 0G2, Canada;2. Carbonix, 690 Mountain Rd, Suite 200, Fort William First Nation, Ontario P7J 1G8 Canada |
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| Abstract: | Along with the great strides that have been made towards understanding cancer, has come a realization of the complexity of molecular events that lead to malignancy. Proteomics-based approaches, which enable the quantitative investigation of both cellular protein expression levels and protein–protein interactions involved in signaling networks, promise to define the molecules controlling the processes involved in cancer. |
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