Lack of physiological stimulation induces decreased proteolytic activity in nerve terminals |
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Authors: | S Gustavsson J -O Karlsson |
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Institution: | (1) Institue of Neurobiology, University of Göteborg, P.O.B. 33 031, S-400 33 Göteborg, Sweden |
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Abstract: | The effect of optic nerve transsection on proteolytic degradation of axonally transported proteins in the superior colliculus of the rabbit was studied. Proteolysis of labeled proteins was determined in vitro in small pieces of the superior colliculus. Within 2 hours after sectioning the optic nerve there was a decreased degradation of slowly transported labeled proteins in the nerve terminals in the superior colliculus.Special Issue dedicated to Prof. Holger Hydén. |
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Keywords: | Nerve activity proteolysis |
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