Synthesis of O-substituted 6-oximes of 16alpha,17alpha-cyclohexanopregn-4-en-3,6,20-triones containing a tritium label at the 1,2-position |
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Authors: | Shevchenko V P Nagaev I Iu Miasoedov N F Kamernitskiĭ A V Levina I S Kulikova L E |
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Affiliation: | Institute of Molecular Genetics, Russian Academy of Sciences, pl. Akademika Kurchatova 2, Moscow, 123182 Russia. nagaev@img.ras.ru |
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Abstract: | ![]() 6-O-(3-Methoxycarbonylpropyl)- and 6-O-(3-carboxypropyl)oximes of 16 alpha,17 alpha-cyclohexanopregn-4-ene-3,6,20-trione labeled by tritium in position 1,2 were synthesized. When using homogenous catalysts, the molar radioactivity of the resulting preparations was 1.5-1.7 PBq/mol. |
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