Enzymic mechanisms involving concomitant transfer and hydrolysis reactions |
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| Authors: | Jean-Marie Frère |
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| Affiliation: | Service de Microbiologie, Faculté de Médecine, Institut de Botanique, Université de Liège, Sart-Tilman, 4000 Liège, Belgium |
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| Abstract: | The kinetic parameters of ten different enzymic mechanisms in which bimolecular transfer reactions occur concomitantly with the hydrolysis of the donor molecule have been studied. The usefulness of these parameters for making a choice of mechanism is discussed. The analysis has been extended to the use of alternative substrates in bimolecular transfer reactions that proceed without the hydrolysis of the donor molecule. |
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