Prediction of an ATP reactive center in the small subunit, gpNu1, of the phage lambda terminase enzyme |
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Authors: | A Becker M Gold |
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Institution: | Department of Medical Genetics, University of Toronto, Canada. |
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Abstract: | The small subunit of the bacteriophage lambda terminase enzyme, the product of the phage's Nu1 gene, is shown to contain amino acid segments homologous to those present in a large number of ATPases. In keeping with these predictions, the purified protein has been found to hydrolyze ATP with a relatively low turnover number. Terminase holoenzyme is a known ATPase, and the biochemical significance of an ATP-interactive center situated in the gpNu1 subunit is discussed. |
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