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Identification of novel Y chromosome encoded transcripts by testis transcriptome analysis of mice with deletions of the Y chromosome long arm |
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| Authors: | Touré Aminata Clemente Emily J Ellis Peter JI Mahadevaiah Shantha K Ojarikre Obah A Ball Penny AF Reynard Louise Loveland Kate L Burgoyne Paul S Affara Nabeel A |
| Affiliation: | (1) Division of Developmental Genetics, MRC National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK;(2) Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK;(3) Monash Institute of Medical Research, Monash University, and The Australian Research Council Centre of Excellence in Biotechnology and Development, Melbourne, Victoria, 3168, Australia |
| Abstract: | BackgroundThe male-specific region of the mouse Y chromosome long arm (MSYq) is comprised largely of repeated DNA, including multiple copies of the spermatid-expressed Ssty gene family. Large deletions of MSYq are associated with sperm head defects for which Ssty deficiency has been presumed to be responsible. |
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