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PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1
Affiliation:1. Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland;2. Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Via Adamello 16, 20139 Milan, Italy;3. Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, 6525 GA Nijmegen, the Netherlands;4. Department of Health Sciences, University of Milan, Via A. di Rudini 8, 20142 Milan, Italy;5. The Netherlands Cancer Institute, Amsterdam, The Netherlands
Abstract:
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  • Keywords:Polycomb  PRC2.1  PRC2.2  H3K27me3  JARID2  Polycomb-like protein  PRC1  CBX2  CBX4  CBX7
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