Rtt107/Esc4 binds silent chromatin and DNA repair proteins using different BRCT motifs |
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| Authors: | David C Zappulla Arindel SR Maharaj Jessica J Connelly Rebecca A Jockusch Rolf Sternglanz |
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| Institution: | (1) Department of Biochemistry and Cellular Biology, Stony Brook University, Stony Brook, NY 11794, USA |
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| Abstract: | Background By screening a plasmid library for proteins that could cause silencing when targeted to the HMR locus in Saccharomyces cerevisiae, we previously reported the identification of Rtt107/Esc4 based on its ability to establish silent chromatin. In this study we aimed to determine the mechanism of Rtt107/Esc4 targeted silencing and also learn more about its
biological functions. |
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