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Statistical analysis of an RNA titration series evaluates microarray precision and sensitivity on a whole-array basis |
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| Authors: | Andrew J Holloway Alicia Oshlack Dileepa S Diyagama David DL Bowtell and Gordon K Smyth |
| Institution: | (1) Ian Potter Foundation Centre for Cancer Genomics and Predictive Medicine, Peter MacCallum Cancer Centre, St Andrew's Place, East Melbourne, Victoria, 3002, Australia;(2) Walter and Eliza Hall Institute, 1G Royal Parade, Parkville, Victoria, 3050, Australia |
| Abstract: | BackgroundConcerns are often raised about the accuracy of microarray technologies and the degree of cross-platform agreement, but there are yet no methods which can unambiguously evaluate precision and sensitivity for these technologies on a whole-array basis. |
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