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Hierarchical modularity of nested bow-ties in metabolic networks |
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| Authors: | Jing Zhao Hong Yu Jian-Hua Luo Zhi-Wei Cao Yi-Xue Li |
| Affiliation: | (1) School of Life Sciences & Technology, Shanghai Jiao Tong University, Shanghai, 200240, China;(2) Shanghai Center for Bioinformation and Technology, Shanghai, 200235, China;(3) Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China;(4) Department of Mathematics, Logistical Engineering University, Chongqing, 400016, China |
| Abstract: | BackgroundThe exploration of the structural topology and the organizing principles of genome-based large-scale metabolic networks is essential for studying possible relations between structure and functionality of metabolic networks. Topological analysis of graph models has often been applied to study the structural characteristics of complex metabolic networks. |
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