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Expression profile analysis of trichostatin A in human gastric cancer cells |
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| Authors: | Hosoon Lee Seongeun Lee Myungin Bæk Hae-Yeong Kim Doo-Il Jeoung |
| Affiliation: | (1) Cancer Research Center, In2Gen Company, Seoul, 110-799, Korea;(2) Plant Metabolism Research Center and Graduate school of Biotechnology, Kyung Hee University, Suwon, 449-701, Korea |
| Abstract: | Trichostatin A (TSA) is an inhibitor of histone deacetylase. cDNA microarray analysis was used to identify genes modulated by TSA. A total of 93 genes were up-regulated and 27 genes down-regulated. The expressions of some of these genes were confirmed by RT-PCR analysis. |
| Keywords: | cDNA microarray gastric cancer cell line histone deacetylase inhibitor trichostatin A (TSA) |
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