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Viral RNA recognition by the Drosophila small interfering RNA pathway
Affiliation:Department of Biochemistry and Immunology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Abstract:Viral RNA is a common activator of antiviral responses. In this review, we dissect the mechanism of viral RNA recognition by the small interfering RNA pathway in Drosophila melanogaster. This antiviral response in fruit flies can help understand general principles of nucleic acid recognition.
Keywords:RNA interference  Small interfering RNA  dsRNA  Viral infection
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