| Abstract: | Phytochemical research of the whole plant Atractylis humilis (Asteraceae family) led to the isolation of one cyclolignan, namely (8R,7′S,8′S)-9′-β-D-glucopyranosyl-3,4′,9-trihydroxy-3′,4,5,5′-tetramethoxy-2,7′-cyclolignan (1), together with thirteen known phytochemicals 2–14 from the ethyl acetate and n-butanol extracts. The structures of all isolated secondary metabolites 1–14 were elucidated by spectroscopic analysis (1D and 2D-NMR, HR-ESI-MS) and measurement of optical rotation α]D, whereas the known compounds were described by spectral comparison data with those published in the literature. This is the first report of lignans in the genus Atractylis. Furthermore, the chemotaxonomic significance of isolates was discussed. |
