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Determination of normal human intrathyroidal iodine in Caracas population
Authors:José Zabala  Nereida Carrión  Miguel Murillo  Mercedes Quintana  José Chirinos  Nelly Seijas  Leopoldo Duarte  Peter Brätter
Affiliation:1. Analytical Chemistry Center, School of Chemistry, Faculty of Science, Central University of Venezuela, P.O. Box 40764, Caracas 1053, Venezuela;2. Forensic Morgue of Bello Monte, Caracas, Venezuela;3. Vargas Hospital of Caracas, Caracas, Venezuela;4. Hahn-Meitner-Institut Berlin, Department Trace Elements in Health and Nutrition, Glienicker Street 100, D14109 Berlin, Germany
Abstract:
This study focuses on the determination of iodine content in healthy thyroid samples on male population from Caracas, Venezuela. Contribution to establish a baseline of iodine content in thyroid glands and hence to compare the iodine thyroid concentration of the Venezuelan population with other countries is also our objective. Male post-mortem individual samples were analyzed using a spectrophotometric flow injection method, based on the Sandell–Kolthoff reaction. The median intrathyroidal iodine concentration was 1443±677 μg/g (wet weight), ranging from 419 to 3430 μg/g, which corresponds to a median of total iodine content of 15±8 mg (ranging from 4 to 37). These results were higher than those values reported in the literature. No correlation of iodine content with age or weight of the healthy gland was found.
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