Polymorphism in regulatory gene sequences |
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Authors: | N A Mitchison |
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Affiliation: | (1) Department of Immunology, Windeyer Institute of Medical Science, University College London Medical School, Cleveland Street, W1P 6DB London, UK |
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Abstract: | The extensive polymorphism revealed in non-coding gene-regulatory sequences, particularly in the immune system, suggests that this type of genetic variation is functionally and evolutionarily far more important than has been suspected, and provides a lead to new therapeutic strategies. |
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