Germination,duplication cycle and septum formation are altered by caffeine,caffeic acid and cinnamic acid in <Emphasis Type="Italic">Aspergillus nidulans</Emphasis> |
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Authors: | P D Yuvamoto S Said |
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Institution: | 1.Departamento de Ciencias Farmaceuticas,FCFRP-Universidade de S?o Paulo,S?o Paulo,Brazil |
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Abstract: | Phytogenous Phenolic and benzene compounds have been described as being responsible for many biological activities including
antifungal effects. The effect of caffeine and cinnamic and caffeic acids on a model fungus, Aspergillus nidulans, was investigated at its initial stage of germination. Conidia did not germinate in the presence of cinnamic acid (1 mM).
Caffeine and caffeic acid exerted a negative effect on germination, on the nuclear duplication cycle and on first septum formation.
The effects of caffeine were dose-dependent; effects of caffeic acid (1 mM) were more intense than those of caffeine (10 mM). |
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Keywords: | Aspergillus nidulans caffeic acid caffeine cinnamic acid |
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