The mechanism of the stimulation of LH production by synthetic LH-releasing hormone (LH-RH) in tissue culture |
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| Authors: | H Ishikawa T Nagayama K Niizuma |
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| Affiliation: | Department of Anatomy Showa University School of Medicine Shinagawa-ku, Tokyo 142 Japan;Metropolitan Arakawa lying-in hospital Machiya, Arakawa-ku, Tokyo 116 Japan |
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| Abstract: | ![]()
Synthetic LH-RH was found to stimulate production of LH by human female adenohypophysis in monolayer culture. This effect occurs at 0.30 μg/2 ml LH-RH. New messenger-RNA synthesis does not have to occur to stimulate the production of LH by the action of synthetic LH-RH in cultures of under 4 days. In cultures of over 4 days, this synthesis must occur in order for LH to be produced by the action of LH-RH. However, new DNA synthesis does not have to occur to stimulate the production of LH by the action of synthetic LH-RH. |
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