LTR retrotransposons and the evolution of dosage compensation in Drosophila |
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| Authors: | Lilya V Matyunina Nathan J Bowen John F McDonald |
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| Affiliation: | (1) School of Biology and Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332, USA |
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| Abstract: | Background Dosage compensation in Drosophila is the epigenetic process by which the expression of genes located on the single X-chromosome of males is elevated to equal
the expression of X-linked genes in females where there are two copies of the X-chromosome. While epigenetic mechanisms are
hypothesized to have evolved originally to silence transposable elements, a connection between transposable elements and the
evolution of dosage compensation has yet to be demonstrated. |
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