RRW: repeated random walks on genome-scale protein networks for local cluster discovery |
| |
| Authors: | Kathy Macropol Tolga Can and Ambuj K Singh |
| |
| Institution: | (1) Department of Computer Science, University of California, Santa Barbara, CA 93106, USA;(2) Department of Computer Engineering, Middle East Technical University, 06531 Ankara, Turkey |
| |
| Abstract: | Background We propose an efficient and biologically sensitive algorithm based on repeated random walks (RRW) for discovering functional
modules, e.g., complexes and pathways, within large-scale protein networks. Compared to existing cluster identification techniques,
RRW implicitly makes use of network topology, edge weights, and long range interactions between proteins. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
