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NMR assignment of PN2-3, a tubulin interaction subdomain of the CPAP protein
Authors:Marie-Jeanne Clément  Philippe Savarin  Jérôme Coutant  Flavio Toma  Patrick Curmi
Affiliation:(1) Laboratoire Structure-Activité des Biomolécules Normales et Pathologiques, INSERM/UEVE U829-Université Evry-Val d’Essonne, Batiment Maupertuis, 91025 Evry, France
Abstract:
We report the NMR assignment of the PN2-3 subdomain of the CPAP protein. It has been previously shown that this motif interacts with tubulin, inhibits microtubule nucleation from the centrosome and depolymerizes taxol-stabilized microtubules. Marie-Jeanne Clément and Philippe Savarin contributed equally.
Keywords:CPAP  Centrosome  Tubulin  Microtubules  NMR assignment
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