| 细胞凋亡（Apoptosis）与癌基因 |
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| 引用本文： | 阎水忠,赵晓航,吴旻.细胞凋亡（Apoptosis）与癌基因[J].生物化学与生物物理进展,1994,21(3):222-224. |
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| 作者姓名： | 阎水忠 赵晓航 吴旻 |
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| 作者单位： | 中国医学科学院肿瘤研究所分子肿瘤学国家重点实验室;中国医学科学院肿瘤研究所分子肿瘤学国家重点实验室;中国医学科学院肿瘤研究所分子肿瘤学国家重点实验室 |
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| 摘 要： | 细胞凋亡是细胞衰老、死亡过程的主要形式.最近研究发现有多种癌基因与抑癌基因参与细胞凋亡过程.因此目前认为癌基因与抑癌基因不仅控制细胞增殖、分化，而且调节细胞凋亡.细胞凋亡受阻或缺陷可能是肿瘤发生的基础之一.
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| 关 键 词： | 细胞凋亡（apoptosis） bcl－2基因 c－myc基因 p53基因 |
| 收稿时间： | 4/8/1993 12:00:00 AM |
| 修稿时间： | 1993/6/10 0:00:00 |
Apoptosis and Oncogenes |
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| Yan Shuizhong,Zhao Xiaohang and Wu Min.Apoptosis and Oncogenes[J].Progress In Biochemistry and Biophysics,1994,21(3):222-224. |
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| Authors: | Yan Shuizhong Zhao Xiaohang and Wu Min |
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| Abstract: | Apoptosis programmed cell death.is a natural form of cell death characterized by active Participated of a cell in the process leading to its own decrepit and death. Recently studies suggested that apoptosis is a result from a set of discrete cellular events that are regulated by a cascade gene expression.Oncogenes and tumor suppressor genes are involved in this regulation. Apoptosis is closely related to cancer.Failure and bolckage of apoptosis in tumor cells could therefore be the fundamental importance in contributing not only to the evasion of physiological countrols on cell numbers, but also to the resistance both to natural defenses and to clinical therapy. |
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| Keywords: | apoptosis bcl-2 gene c-myc gene p53 gene |
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