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硫酸软骨素酶ABC治疗减少大鼠脊髓损伤引起的酪氨酸蛋白激酶A4的表达
引用本文:Liu XM,Kang HY,Xu JW,Sun DH. 硫酸软骨素酶ABC治疗减少大鼠脊髓损伤引起的酪氨酸蛋白激酶A4的表达[J]. 生理学报, 2011, 63(6): 498-504
作者姓名:Liu XM  Kang HY  Xu JW  Sun DH
作者单位:河南漯河医学高等专科学校;
基金项目:supported by the Natural Science Research Project of Education Department of Henan Province,China(No.2010C310004)
摘    要:
本研究旨在探讨大鼠脊髓损伤(spinal cord impairment,SCI)后硫酸软骨素酶ABC (chondroitinase ABC,ChABC)对酪氨酸蛋白激酶A4 (ephrin A4,EphA4)表达变化的影响.选取成年雌性SD大鼠,随机分为假手术组、生理盐水(NS)组和ChABC组.NS组和ChABC...

关 键 词:脊髓损伤  硫酸软骨素酶ABC  酪氨酸蛋白激酶A4

Inhibitory effect of chondroitinase ABC on ephrin A4 expression after spinal cord injury in rats
Liu Xi-Min,Kang Hong-Yu,Xu Ji-Wei,Sun Dan-Hua. Inhibitory effect of chondroitinase ABC on ephrin A4 expression after spinal cord injury in rats[J]. Acta Physiologica Sinica, 2011, 63(6): 498-504
Authors:Liu Xi-Min  Kang Hong-Yu  Xu Ji-Wei  Sun Dan-Hua
Affiliation:LIU Xi-Min,KANG Hong-Yu,XU Ji-Wei,SUN Dan-Hua Luohe Medical College,Luohe 462002,China
Abstract:
The aim of the study was to investigate the effect of chondroitinase ABC (ChABC) on ephrin A4 (EphA4) expression after spinal cord impairment (SCI) in rats.Adult female SD rats were randomly divided into three groups:ChABC group,normal saline (NS) group and sham group.In the ChABC and NS group,the SCI model was produced by the spinal cord hemisection.The rats in sham group received sham operation without the spinal hemisection.ChABC and NS groups were intrathecally injected with ChABC and normal saline,resp...
Keywords:chondroitinase ABC  spinal cord injury  ephrin A4  
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