| 薏米黄酒的急性毒性研究 |
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| 引用本文： | 吴海,申可佳,谭周进,朱伟,李珊,蔡锐.薏米黄酒的急性毒性研究[J].现代生物医学进展,2011,11(5):867-869. |
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| 作者姓名： | 吴海 申可佳 谭周进 朱伟 李珊 蔡锐 |
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| 作者单位： | 1. 湖南中医药大学2009级硕士研究生班,湖南,长沙,410208
2. 湖南中医药大学基础医学院,湖南,长沙,410208 |
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| 基金项目： | 湖南新化县蚩尤酒厂课题，长沙市科技局项目 |
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| 摘 要： | 目的:研究薏米黄酒的急性毒性,评价该酒的食用安全性。方法:以ICR小鼠为受试对象,一次性给予最大剂量,观察薏米黄酒对小鼠的急性毒性反应,测定薏米黄酒的LD50和最大耐受剂量。结果:小鼠无一只死亡,无法测出LD50,最大耐受量大于20400 mg/kg。结论:实验检测表明,该黄酒无毒,为薏米黄酒的应用提供了毒理学依据。
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| 关 键 词： | 薏米黄酒 急性毒性 动物实验 |
Acute Toxicity Test of Coix Seed Yellow Rice Wine |
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| WU Hai,SHEN Ke-ji,TAN Zhou-jin,ZHU Wei,LI Shan,CAI Rui.Acute Toxicity Test of Coix Seed Yellow Rice Wine[J].Progress in Modern Biomedicine,2011,11(5):867-869. |
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| Authors: | WU Hai SHEN Ke-ji TAN Zhou-jin ZHU Wei LI Shan CAI Rui |
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| Institution: | 1 2009 Postgraduate Courses,Hunan University of Traditional Chinese Medicine,Changsha,Hunan,China,410208; 2 College of Basic Medicine,TCM University of Hunan,Changsha,China,410208) |
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| Abstract: | Objective: To investigate the acute toxicity of coix seed yellow rice wine, and to evaluate the consumption safety of the
yellow rice wine. Methods: Maximum dose was given once to ICR mice for detecting acute toxicity of the mice, the LD50 ofthe coix seed
rice wine. The largest quantity of administration was detected. Results: There were no mice death and LD50 of the yellow rice wine was
not detected. The largest amount of the drug was more than 20400 mg/kg. Conclusion: The rice wine was safe, which provides a
toxicological basis for the application of the wine. |
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| Keywords: | Coix seed yellow rice wine Acute toxicitytest Animal experiments |
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