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Induction of a neutral protease from rat intestine by a dietary manipulation
Authors:Kenji Wada  Tetsuaki Abe  Yasuko Sawai  Kinji Tsukada
Affiliation:Department of Pathological Biochemistry, Medical Research Institute, Tokyo Medical and Dental University, Kandasurugadai, Chiyoda-ku, Tokyo 101, Japan
Abstract:
The activity of a neutral protease is increased in soluble fractions from the intestine of rats after a shift from a protein-free to a casein mash and an injection of triiodothyronine. The increased activity is prevented by the administration of cycloheximide. The time curve of the response of the protease activity in intestine is similar to that of liver DNA synthesis after a shift to 50% casein and triiodothyronine.
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