Solvation of platinum anti-cancer drugs in methanol-water mixtures |
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| Authors: | John Burgess Duncan N Drasdo Marttand S Patel |
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| Institution: | (1) Chemistry Department, University of Leicester, Leicester, UK;(2) Chemistry Department, University of Leicester, LE1 7RH Leicester, UK |
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| Abstract: | Solubilities and transfer chemical potentials of carboplatin, cisplatin, iproplatin, and several related platinum complexes have been determined in methanol-water mixtures. the range of solvation behaviour is discussed in relation to possible oral administration of complexes of this type. |
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| Keywords: | anticancer drugs platinum complexes solvation |
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