Central administration of galanin stimulates feeding behavior in chicks |
| |
| Authors: | Tachibana Tetsuya Mori Miyabi Khan Md Sakirul Islam Ueda Hiroshi Sugahara Kunio Hiramatsu Kohzy |
| |
| Affiliation: | aLaboratory of Animal Production, Department of Agrobiological Science, Faculty of Agriculture, Ehime University, Matsuyama 790-8566, Japan;bLaboratory of Nutritional Biochemistry, Department of Animal Science, Faculty of Agriculture, Utsunomiya University, Utsunomiya, Tochigi 321-8505, Japan;cLaboratory of Functional Anatomy, Faculty of Agriculture, Shinshu University, Minamiminowa, Kami-ina, Nagano 399-4598, Japan |
| |
| Abstract: | Galanin is recognized as one of the orexigenic peptides in the brain of mammals and fishes. The amino acid sequence of chicken galanin and its distribution in the brain are similar to those of mammals, suggesting that the brain galanin might be related to feeding regulation in chicks. The purpose of the present study was to investigate whether intracerebroventricular (ICV) injection of galanin affected feeding behavior of chicks (Gallus gallus). The injection of galanin increased food intake of layer and broiler chicks. We also found that the galanin-induced feeding behavior was attenuated in layer chicks by the co-injection of yohimbine and beta-funaltrexamine, which are the antagonists of adrenergic alpha-2 receptor and opioid mu-receptor, respectively. It is therefore possible that the orexigenic effect of galanin is mediated by these receptors. |
| |
| Keywords: | Adrenergic alpha-2 receptor Chicks Feeding Galanin Opioid mu-receptor |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
