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Conversion of glucose to cortalcerone via glucosone by Corticium caeruleum
Authors:Marie-Antoinette Baute  Robert Baute  Gérard Deffieux  Marie-José Filleau
Institution:1. Laboratoire de Cryptogamie et Microbiologie industrielle, Rue Leyteire, 33000 Bordeaux, France;2. Laboratoire de Chimie analytique, Faculté de Pharmacie, Université de Bordeaux II, Rue Leyteire, 33000 Bordeaux, France
Abstract:Glucose was the sole compound to be converted to cortalcerone by ‘activated’ blue mycelia of Corticium caeruleum; the first step of this transformation was shown to be the oxidation of glucose to glucosone. The conversion of glucosone to cortalcerone implies a novel enzymatic dehydrating activity which could be specific for C. caeruleum.
Keywords:fungus  antibiotic  cortalcerone  2-hydroxy-6H-3-pyrone-2-carboxaldehyde hydrate  bioconversion  glucose  glucosone  osones  enzymatic activity  
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