Biotransformation of 2-(4-methoxybenzyl)-l-cyclohexanone by cell cultures ofSolatium aviculare |
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Authors: | Z Wimmer T Macek T Vaněk L Streinz M Romaňuk |
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Institution: | (1) Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, Flemingovo n. 2, 166 10 Praha 6, Czechoslovakia |
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Abstract: | During the search for compounds with insect juvenile hormone activity, the biotransformation of 2-(4-methoxybenzyl)-l-cyclohexanone,
of 2-(4-methoxybenzyl)-l-cyclohexanone ethylene acetal and of both isomers of 2-(4-methoxybenzyl)-l-cyclohexanol by plant
cells was examined. The compounds were metabolized by cell suspension culture of Solatium aviculare Forst. The reaction conditions
were optimized and the metabolic products isolated and identified. A scheme of biotransformation pathway has been proposed. |
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