In vitro anti-inflammatory and antimicrobial potential of leaf extract from Artemisia nilagirica (Clarke) Pamp |
| |
Authors: | P Parameswari R Devika P Vijayaraghavan |
| |
Institution: | 1. Department of Biotechnology, Sathyabama University, Chennai 600 119, Tamil Nadu, India;2. Department of Biotechnology, Aarupadai Veedu Institute of Technology, Paiyanoor 603 104, Tamil Nadu, India;3. Centre for Marine Science and Technology, Manonmaniam Sundaranar University, Rajakkamangalam 629 502, Kanyakumari District, Tamil Nadu, India |
| |
Abstract: | In the present investigation, the bioactive compounds from the leaf extract of Artemisia nilagirica showed potent anti-inflammatory and antimicrobial activity. The leaf extract showed a maximum protection of human red blood cells (HRBC) with 74.63% at 20?µg/mL concentration, and the minimum hemolysis was 25.37% in a hypotonic solution with diclofenac as the control. The in vitro antimicrobial activity of plant extract against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhi, Proteus vulgaris, Yersinia enterocolitica, Bacillus subtilis, and Candida albicans was evaluated at various concentrations (50, 100, 150, and 200?µg). The maximum zone of inhibition was observed against P. aeruginosa followed by B. subtilis, S. typhi, S. aureus and E. coli. The leaf extract also showed potent activity against C. albicans. |
| |
Keywords: | Medicinal plants Anti-inflammatory Anti-bacterial Antifungal |
本文献已被 ScienceDirect 等数据库收录! |
|