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Genetic Ablation of miR-33 Increases Food Intake,Enhances Adipose Tissue Expansion,and Promotes Obesity and Insulin Resistance
Authors:Nathan L Price  Abhishek K Singh  Noemi Rotllan  Leigh Goedeke  Allison Wing  Alberto Canfrán-Duque  Alberto Diaz-Ruiz  Elisa Araldi  Ángel Baldán  Joao-Paulo Camporez  Yajaira Suárez  Matthew S Rodeheffer  Gerald I Shulman  Rafael de Cabo  Carlos Fernández-Hernando
Institution:1. Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA;2. Integrative Cell Signaling and Neurobiology of Metabolism Program, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA;3. Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA;4. Department of Molecular, Cellular, and Developmental Biology, Yale University School of Medicine, New Haven, CT, USA;5. Edward A. Doisy Department of Biochemistry and Molecular Biology and Center for Cardiovascular Research, Saint Louis University School of Medicine, St. Louis, MO, USA;6. Department of Pathology, Yale University School of Medicine, New Haven, CT, USA;7. Department of Cellular and Molecular Physiology and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, USA;8. Translational Gerontology Branch, National Institute of Aging, NIH, Baltimore, MD, USA
Abstract:
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  • Keywords:miR-33  obesity  insulin-resistance  food-consumption  metabolism  micro-RNA  adipocyte  pair-feeding  diabetes
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