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Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition
Authors:Clara Lopes Novo  Biola-Maria Javierre  Jonathan Cairns  Anne Segonds-Pichon  Steven W Wingett  Paula Freire-Pritchett  Mayra Furlan-Magaril  Stefan Schoenfelder  Peter Fraser  Peter J Rugg-Gunn
Institution:1. Epigenetics Programme, Babraham Institute, Cambridge CB22 3AT, UK;2. Nuclear Dynamics Programme, Babraham Institute, Cambridge CB22 3AT, UK;3. Bioinformatics Group, Babraham Institute, Cambridge CB22 3AT, UK;4. Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA;5. Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 1QR, UK
Abstract:
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  • Keywords:epigenetics  genome organization  chromatin looping  gene regulation  pluripotency  differentiation  promoter capture Hi-C
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