Molecular evolution of a repetitive region within the per gene of Drosophila |
| |
Authors: | Peixoto AA; Campesan S; Costa R; Kyriacou CP |
| |
Institution: | Department of Genetics, University of Leicester, United Kingdom. |
| |
Abstract: | The clock gene period (per) controls a number of biological rhythms in
Drosophila. In D. melanogaster, per has a repetitive region that encodes a
number of alternating threonine-glycine residues. We sequenced and compared
this region from several different Drosophila species belonging to various
groups within the Drosophila and Sophophora subgenera. This part of per
shows a great variability in both DNA sequence and length. Furthermore,
analysis of the data suggests that changes in the length of this variable
region might be associated with amino acid replacements in the more
conserved flanking sequences.
|
| |
Keywords: | |
本文献已被 Oxford 等数据库收录! |
|