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Mutant TDP-43 Causes Early-Stage Dose-Dependent Motor Neuron Degeneration in a TARDBP Knockin Mouse Model of ALS |
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| Authors: | Sarah Y. Ebstein Ilona Yagudayeva Neil A. Shneider |
| Affiliation: | 1. Department of Neurology, Center for Motor Neuron Biology and Disease, Columbia University Irving Medical Center, 630 W 168th Street, P&S Building, Room 5-423, New York, NY 10032, USA;2. Eleanor and Lou Gehrig ALS Center, Columbia University Irving Medical Center, 630 W 168th Street, P&S Building, Room 5-423, New York, NY 10032, USA |
| Abstract: |  |
| Keywords: | TARDBP TDP-43 amyotrophic lateral sclerosis knockin mouse motor neuron disease neurodegeneration muscle denervation |
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