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Adenoviral delivery of dominant‐negative transforming growth factor β type II receptor up‐regulates transcriptional repressor SKI‐like oncogene,decreases matrix metalloproteinase 2 in hepatic stellate cell and prevents liver fibrosis in rats
Authors:Ana Marquez‐Aguirre  Ana Sandoval‐Rodriguez  Jaime Gonzalez‐Cuevas  Miriam Bueno‐ Topete  Jose Navarro‐Partida  Immaculada Arellano‐Olivera  Silvia Lucano‐Landeros  Juan Armendariz‐Borunda
Affiliation:1. Institute for Molecular Biology in Medicine and Gene Therapy, University of Guadalajara, Department of Molecular Biology and Genomics, Guadalajara, Jalisco, Mexico;2. OPD Hospital Civil de Guadalajara, Guadalajara, Jalisco, Mexico
Abstract:
Keywords:hepatic stellate cells  liver fibrosis  MMP‐2  SnoN  TGF‐β   signaling  thioacetamide
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