| 髓样细胞在肿瘤血管生成过程中的作用 |
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| 引用本文： | 华荣,袁志刚,丁晔,许淑茹,舒伟. 髓样细胞在肿瘤血管生成过程中的作用[J]. 生命科学, 2010, 0(8): 806-810 |
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| 作者姓名： | 华荣 袁志刚 丁晔 许淑茹 舒伟 |
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| 作者单位： | 广西医科大学基础医学院,南宁530021 |
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| 基金项目： | 国家自然科学基金项目（30860125） |
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| 摘 要： | 肿瘤血管生成在肿瘤的发展过程中起着关键作用。外周循环血中存在的一些髓样细胞,如巨噬细胞、中性粒细胞、酸性粒细胞、肥大细胞和树突状细胞等具有多方面的能力,被募集到肿瘤组织中,在肿瘤微环境中促进肿瘤的血管生成。这些髓样细胞在肿瘤血管生成过程中起重要的作用。该文对这些不同类型细胞促进肿瘤血管生成的作用进行了论述。
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| 关 键 词： | 肿瘤血管生成 髓样细胞 肿瘤微环境 |
The role of myeloid cells in the promotion of tumour angiogenesis |
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| HUA Rong,YUAN Zhi-gang,DING Ye,XU Shu-ru,SHU Wei. The role of myeloid cells in the promotion of tumour angiogenesis[J]. Chinese Bulletin of Life Sciences, 2010, 0(8): 806-810 |
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| Authors: | HUA Rong YUAN Zhi-gang DING Ye XU Shu-ru SHU Wei |
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| Affiliation: | (School of Pre-clinical Science,Guangxi Medical University,Nanning 530021,China) |
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| Abstract: | Tumour angiogenesis is a crucial step in tumour development.Bone marrow-derived myeloid cells,such as macrophages,neutrophils,eosinophils,mast cells and dendritic cells,have an important role in regulat-ing the formation and maintenance of blood vessels in the tumour microenvironment.In this review the evi-dence for each of these cell types driving tumour angiogenesis is outlined,along with the mechanisms regulat-ing their recruitment and activation by the tumour. |
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| Keywords: | Tumour angiogenesis myeloid cells tumour microenvironment |
| 本文献已被 CNKI 维普 等数据库收录！ |
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