Influence of cold exposure on liver amino acid metabolism enzymes of the rat |
| |
| Authors: | F J López-Soriano M Alemany |
| |
| Affiliation: | Departament de Bioquímica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Spain. |
| |
| Abstract: | The activities of alanine, aspartate and branched-chain amino acid transaminases, glutamate dehydrogenase, glutamine synthetase and adenylate deaminase have been studied in liver of male rats exposed [12 hours at 4 degrees C] or acclimated [15 days at 4 degrees C] to cold temperature. Cold temperature induced an increase of the activities of glutamate dehydrogenase and alanine and aspartate transaminases both in cold-exposed and cold-acclimated animals; adenylate deaminase activity diminished after 15-day cold acclimation. There were not significant changes induced by cold temperature in the activities of the other two enzymes studied. These results agree with a possible direct implication of amino acid utilization by the liver in the context of the overall thermogenic response to cold temperature. |
| |
| Keywords: | |
|
|
