Trace elements in hair of blackfoot disease |
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| Authors: | T C Pan T H Lin C L Tseng M H Yang C W Huang |
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| Institution: | (1) School of Chemistry, Kaohsiung Medical College, 807 Kaohsiung, Taiwan, R.O.C.;(2) School of Technology for Medical Sciences, Kaohsiung Medical College, 807 Kaohsiung, Taiwan, R.O.C.;(3) Institute of Nuclear Science, National Tsing Hua University, 300 Hsinchu, Taiwan, R.O.C.;(4) Institute of Chemistry, Chung Yuan Christian University, 320 Chung-Li, Taiwan, R.O.C. |
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| Abstract: | Blackfoot disease is a peripheral vascular disease resulting in gangrene of the lower extremities. Though extensive epidemiological
study has implicated that high arsenic content in artesian well water of the endemic area, bears some important connection
with the disease, the etiology of the disease is still unknown. In this study, attention is paid to multielement determination
in order to find out whether the trace elements in hair of Blackfoot disease patients are different from those of the controls.
Experimental results indicate that the concentrations of As and Se in hair of patients are significantly higher than those
of the controls, but Ca and Zn are significantly lower than those of the controls. The possible connection of these elements
with the etiology of the disease is discussed. |
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| Keywords: | Blackfoot disease neutron activation analysis trace elements hair specimens |
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