The clinical implications of adult-onset henoch-schonelin purpura |
| |
Authors: | Jithpratuck Warit Elshenawy Yasmin Saleh Hana Youngberg George Chi David S Krishnaswamy Guha |
| |
Institution: | Departments of Internal Medicine, Quillen College of Medicine, East Tennessee State University, TN, USA. krishnas@mail.etsu.edu. |
| |
Abstract: | Henoch-Schonlein Purpura (HSP) is a small vessel vasculitis mediated by IgA-immune complex deposition. It is characterized by the clinical tetrad of non-thrombocytopenic palpable purpura, abdominal pain, arthritis and renal involvement. Pathologically, it can be considered a form of immune complex-mediated leukocytoclastic vasculitis (LCV) involving the skin and other organs. Though it primarily affects children (over 90% of cases), the occurrence in adults has been rarely reported. Management often involves the use of immunomodulatory or immune-suppressive regimens. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|