Coumarins from the Malagasy Cedrelopsis rakotozafyi Cheek and Lescot (Rutaceae) |
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| Affiliation: | 1. Department of Chemistry, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, GU2 7XH Surrey, UK;2. Malaria Research Unit, Institut Pasteur de Madagascar, BP 1274 Antananarivo (101), Madagascar;3. School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4041, South Africa;1. State Key Laboratory of Structural Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China;2. School of Ocean Science and Technology, Dalian University of Technology, Panjin 124221, China;3. School of Mechanical Engineering, Dalian University of Technology, Dalian 116024, China;1. National Engineering Research Center of Maricultural Facilities of China, College of Marine Science and Technology, Zhejiang Ocean University, Zhoushan 316004, PR China;2. Department of Aquatic Science, Faculty of Science, Burapha University, Chon Buri 20131, Thailand;1. Laboratory of Medicinal Chemistry, Federal University of Alagoas, Alagoas, Brazil;2. Institute of Chemistry and Biotechnology, Federal University of Alagoas, Alagoas, Brazil;3. Institute of Pharmacy and Biochemistry, Johannes Gutenberg University of Mainz, Mainz, Germany;1. Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, People’s Republic of China;2. Institute of Traditional Chinese Medicine & Natural Products, and Guangdong Provincial Engineering Research Center for Modernazation of TCM, College of Pharmacy, Jinan University, Guangzhou 510632, People’s Republic of China;3. State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao SAR, People’s Republic of China |
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| Abstract: | A phytochemical analysis of the bark of the Malagasy Cedrelopsis rakotozafyi Cheek and Lescot (Rutaceae) yielded the novel 8-hydroxy-7-methoxy-6-(2R-hydroxy-3-methylbut-3-enoxy)-2H-1-benzopyran-2-one, and 7-hydroxy-6-(2R-hydroxy-3-methylbut-3-enoxy)-2H-1-benzopyran-2-one, 5,6,7-trimethoxy-2H-1-benzopyran-2-one, scoparone, scopoletin, lupeol and β-amyrin. The placement of Cedrelopsis within the Rutaceae is supported phytochemically by the typically Rutaceous coumarins isolated. |
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| Keywords: | Coumarins 5,6,7-Trimethoxy-2H-1-benzopyran-2-one |
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