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Synthesis and biological evaluation of novel 4"-alkoxy avermectin derivatives
Authors:Nagai Kenichiro  Shiomi Kazuro  Sunazuka Toshiaki  Harder Achim  Turberg Andreas  Omura Satoshi
Affiliation:Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University and The Kitasato Institute, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Abstract:Novel 4"-alkoxy avermectin derivatives were synthesized via rhodium carbenoid mediated O-H insertion reaction and tested for antiparasite activity against Artemia salina and Caenorhabditis elegans.
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