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Vault particles: a new generation of delivery nanodevices

Authors:	Arnau Casañas Pablo Guerra Ignasi Fita Núria Verdaguer

Institution:	1. State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 210029, China;2. Nanjing Institute of Environmental Sciences/Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection, Nanjing 210042, China

Abstract:	Download : Download high-res image (270KB) Download : Download full-size image Highlights? Vault particles can be exploited in nanobiotechnology as drug delivery nanodevices. ? The structural information of vaults would serve as a guide for rational engineering. ? The dynamic structure of vaults may be controlled for manipulation of drug release. ? Engineered vaults allow specific cell targeting and controlled encapsulation.

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