Isolation,characterization, and bioactivity of endophytic fungi of <Emphasis Type="Italic">Tylophora indica</Emphasis> |
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Authors: | Susheel Kumar Nutan Kaushik Ruangelie Edrada-Ebel Rainer Ebel Peter Proksch |
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Institution: | 1.TERI University,Vasant Kunj, New Delhi,India;2.The Energy and Resources Institute (TERI), India Habitat Centre,New Delhi,India;3.Institut für Pharmazeutische Biologie und Biotechnologie, Heinrich-Heine-Universit?t,Düsseldorf,Germany;4.Department of Chemistry,University of Aberdeen,Scotland,UK |
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Abstract: | Dothediomycetes sp., Alternaria
tenuissima, Thielavia
subthermophila, Alternaria sp., Nigrospora
oryzae, Colletotrichum truncatum, and Chaetomium sp. were isolated as endophytic fungi from leaves and stems of the medicinal plant, Tylophora indica, based on rDNA sequencing of ITS region and microscopic examination. Alternaria
tenuissima, Colletotrichum truncatum, and Alternaria sp. were found to be active against both Sclerotinia
sclerotiorum and Fusarium
oxysporum. Chaetomium sp. showed very mild activity against Sclerotinia
sclerotiorum and Fusarium
oxysporum. Whereas Dothideomycete sp. and Thielavia
subthermophila showed high activity against Sclerotinia
sclerotiorum. Methanol extract of Dothediomycetes sp. showed 66.5% growth inhibition (GI) at 500 μg/ml. |
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