Drosophila development: RNA interference ab ovo |
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Authors: | Chekulaeva Marina Ephrussi Anne |
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Affiliation: | European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany. chekulae@emble.de |
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Abstract: | A novel protein required for RNA interference in Drosophila, Armitage, was identified in a screen for genes involved in embryonic axis formation. In armitage mutants, oocyte polarity and the regulation of oskar mRNA translation are impaired, suggesting that RNA silencing regulates the first steps of Drosophila development. |
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