Changes in cell proliferation,but not in vascularisation are characteristic for human endometrium in different reproductive failures - a pilot study |
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| Authors: | Ariane Germeyer Michael von Wolff Julia Jauckus Thomas Strowitzki Tanuj Sharma Anna T Grazul-Bilska |
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| Institution: | (1) Department of Gynecological Endocrinology and Reproductive Medicine, University Hospital Heidelberg, Heidelberg, Germany;(2) Department of Gynecological Endocrinology and Reproductive Medicine, University Hospital Berne, Berne, Switzerland;(3) Department of Animal Sciences and Cell Biology Center, North Dakota State University, Fargo, North Dakota, USA |
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| Abstract: | Background Reproductive failure, determined as recurrent spontaneous abortions (RSA) or recurrent implantation failure (RIF) in women
is not well understood. Several factors, including embryo quality, and cellular and molecular changes in endometrium may contribute
to the insufficient feto-maternal interaction resulting in reproductive failure. Prior clinical studies suggest an inadequate
endometrial growth and development of the endometrium, leading to a lesser endometrial thickness. |
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